Interface guided phenotyping of coding variants in the transcription factor RUNX1 with SEUSS
Dr. Hannah Carter (UCSD) discusses how she and her colleagues employed SEUSS, a Perturb-seq-like methodology, to generate and assay mutations at physical interfaces of the RUNX1 Runt domain.
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Mutation-Specific Epigenetic Reprogramming of Hematopoietic Stem Cells in AML
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